Cristian A Carvajal Selected Research

Oxidoreductases (Dehydrogenase)

1/2016	Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children.
1/2015	Epigenetics and arterial hypertension: the challenge of emerging evidence.
3/2014	Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.
4/2013	Age-related changes in 11β-hydroxysteroid dehydrogenase type 2 activity in normotensive subjects.
5/2012	11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.
3/2012	Overexpression of 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue and portal hypercortisolism in non-alcoholic fatty liver disease.
12/2011	Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and β cell dysfunction.
12/2011	Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients.
2/2010	11β-Hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in the pathogenia of essential hypertension.

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Cristian A Carvajal Research Topics

Disease

29	Hypertension (High Blood Pressure) 03/2022 - 06/2003
15	Hyperaldosteronism (Conn Syndrome) 03/2022 - 10/2007
5	Familial Hyperaldosteronism 11/2021 - 09/2008
5	Essential Hypertension 01/2021 - 07/2007
5	Insulin Resistance 03/2016 - 10/2007
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 12/2011
4	Obesity 03/2016 - 01/2010
4	Inflammation (Inflammations) 03/2016 - 09/2008
3	Dyslipidemias (Dyslipidemia) 03/2016 - 01/2010
3	Cushing Syndrome 03/2012 - 12/2011
2	Hypokalemia 01/2019 - 06/2003
2	Apparent Mineralocorticoid Excess Syndrome 01/2018 - 01/2016
2	Heart Diseases (Heart Disease) 01/2017 - 10/2010
2	Abdominal Obesity 12/2011 - 12/2011
1	Glucocorticoid Receptor Deficiency 01/2022
1	Hypotension (Low Blood Pressure) 01/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2016
1	Stroke (Strokes) 10/2016
1	Noncommunicable Diseases 10/2016
1	Morbid Obesity 01/2016
1	Type 2 Diabetes Mellitus (MODY) 03/2014
1	Non-alcoholic Fatty Liver Disease 03/2012
1	Hypoadiponectinemia 12/2011
1	Hyperinsulinism (Hyperinsulinemia) 12/2011
1	Fibrosis (Cirrhosis) 10/2010
1	Adenoma (Adenomas) 07/2008
1	Mood Disorders (Mood Disorder) 06/2007
1	Treatment-Resistant Depressive Disorder 06/2007
1	Neoplasms (Cancer) 08/2004
1	Hyperplasia 02/2004

Drug/Important Bio-Agent (IBA)

16	AldosteroneIBA 03/2022 - 10/2007
14	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2020 - 06/2003
11	ReninIBA 03/2022 - 06/2003
10	Cortisone FDA Link 01/2020 - 01/2005
9	Oxidoreductases (Dehydrogenase)IBA 01/2016 - 02/2010
8	EnzymesIBA 11/2021 - 06/2003
8	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2020 - 06/2003
6	MineralocorticoidsIBA 01/2022 - 01/2016
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2016
4	C-Reactive ProteinIBA 01/2022 - 09/2008
4	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 11/2021 - 06/2011
4	methylamphotericin B (AME)IBA 01/2021 - 01/2018
3	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 08/2013 - 06/2011
3	GlucocorticoidsIBA 12/2011 - 09/2008
2	AdiponectinIBA 01/2022 - 01/2016
2	Adrenocorticotropic Hormone (ACTH)FDA Link 11/2021 - 09/2008
2	Progesterone FDA LinkGeneric 11/2021 - 08/2013
2	Hormones (Hormone)IBA 01/2017 - 03/2016
2	SteroidsIBA 01/2017 - 02/2004
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 10/2007
2	Interleukin-6 (Interleukin 6)IBA 01/2016 - 03/2014
2	Metalloproteases (Metalloproteinases)IBA 03/2014 - 09/2008
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2022
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	AdipokinesIBA 01/2022
1	Testosterone (Sustanon)FDA Link 11/2021
1	Angiotensin IIIBA 11/2021
1	Estradiol (Delestrogen)FDA LinkGeneric 11/2021
1	PotassiumIBA 01/2020
1	SodiumIBA 10/2016
1	LeptinIBA 03/2016
1	Plasminogen InactivatorsIBA 01/2016
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2016
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2016
1	SaltsIBA 06/2015
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2015
1	AngiotensinogenIBA 01/2015
1	adducinIBA 01/2015
1	Protein Isoforms (Isoforms)IBA 03/2014
1	GTP Phosphohydrolases (GTPases)IBA 03/2014
1	Malondialdehyde (Propanedial)IBA 03/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2014
1	Interleukin-8 (Interleukin 8)IBA 03/2014
1	Plasminogen Activator Inhibitor 1IBA 03/2014
1	TetrahydrocortisoneIBA 01/2014
1	TetrahydrocortisolIBA 01/2014
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2012
1	18-hydroxycortisolIBA 01/2012
1	11-beta-Hydroxysteroid Dehydrogenase Type 1IBA 01/2010
1	Chymosin (Rennin)IBA 09/2008
1	Ligases (Synthetase)IBA 09/2008
1	Epithelial Sodium ChannelsIBA 07/2007
1	Messenger RNA (mRNA)IBA 07/2007
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 06/2007
1	Thyroid HormonesIBA 06/2007
1	NucleotidesIBA 08/2004
1	steroidogenic acute regulatory proteinIBA 02/2004
1	11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA 06/2003

Therapy/Procedure

2	Therapeutics 03/2016 - 06/2007